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Term Definition
CRPA

Carbapenem-resistant Pseudomonas aeruginosa

cUTI

Complicated urinary tract infection

CxO’s

CEO: Chief Executive Officer, CIO: Chief Intelligence/IT Officer, CFO: Chief Financial Officer, CMO: Chief Marketing Officer, CSO: Chief Scientific Officer, CTO: Chief Technical Officer etc.

DBO

Diazabicyclooctane

DDD

Defined daily doses

DFI

Diabetic foot infection

DFO

Diabetic foot osteomyelitis

DNDi

Drugs for Neglected Diseases Initiative: A non-profit research and development (R&D) organization that develops new treatments for neglected diseases.

DRG

Diagnostic-related groups

DS-TB

Drug-sensitive tuberculosis

EARSS

European Antimicrobial Resistance Surveillance System

EBA

Early bactericidal activity

ECDC

European Centre for Disease Prevention and Control

ECOFF

Epidemiological cut-off values

Ecological

At the bacterial level, the ecological aspects refer to the competition between non-resistant strains and resistant strains of infectious bacteria. In untreated patients, non-resistant bacteria have a competitive advantage over the resistant strains that keeps the numbers of resistant bacteria extremely low. During treatment, however, the antibiotics kill off the normal bacteria and that allows the resistant strain to take over. As a result, a patient on antibiotics becomes a potential source of infection with resistant bacteria. This continues as long as the treatment lasts. After the treatment is ended, the population of non-resistant bacteria of all types rebounds and the population of resistant bacteria begins to drop until the patient ceases acting as a source. The clinical significance of this is that antibiotics that may benefit the individual (actual) patient may create a serious and detrimental problem to the general patient community.

EEA

European Economic Area

EFSA

European Food Safety Authority

EHR/EMR/EPR

Electronic Health Records/Electr. Medical Records/Electr. Patient Records; PCHR’s refer to so-called patient- or personally controlled health records

EMA

European Medicines Agency

EMEA

European Medicines Agency

ENABLE

European Gram Negative AntiBacteriaL Engine: www.nd4bb-enable.eu

EOT

End of treatment

ESAC-Net

European Surveillance of Antimicrobial Consumption Network

ESBL

Extended-spectrum beta-lactamases (enzyme produced by ‘superbug’ bacteria making them resistant to common antibiotics such as penicillins and cephalosporins)

ESC

Extended spectrum cephalosporin

ESCMID

European Society for Clinical Microbiology and Infectious Diseases

ESUAvet

European Sales and Use of Antimicrobials for Veterinary Medicine

ESVAC

European Surveillance of Veterinary Antimicrobial Consumption

EU

European Union

EUCAST

European Committee on Antimicrobial Susceptibility Testing

FAO

Food and Agriculture Organization (UN)

FDA

Food and Drug Administration, USA

GARDP

Global Antibiotic Research and Development Partnership

GLASS

Global Antimicrobial Resistance and Use Surveillance System

GLOPID-R

Global Research Collaboration for Infectious Disease Preparedness

GP

General practitioner

GR

Genotypic resistance

Gram

Gram-negative indicates a group of bacteria that become red when the bacterial cells are treated using the Gram stain method. This response is based on the chemical and physical properties of their cell walls and is used to identify the type of bacteria. Gram-positive indicates a group of bacteria that become blue when the bacterial cells are treated with the Gram stain.

HABP

Hospital-acquired bacterial pneumonia

HAI

Healthcare-associated infections

HAP

Hospital-acquired pneumonia

HCAP

Healthcare-associated pneumonia

HFMA

Healthcare Financial Management Association

HIS

Hospital Information System

HITSP

Healthcare Information Technology Standards Panel, USA

HMP

Human medicinal product

HPA

Health Protection Agency, UK equivalent of the American CDC

ICU

Intensive care unit

IFR

Institut for Rationel Farmakoterapi

IHI

Institute for Healthcare Improvement