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The presence of NDM gives the bacteria its resistant bite because this enzyme is less common in the US than elsewhere in the world and is resistant to most available antibiotics, according to the researchers. In a study published in the Annals of Internal Medicine, Danielle Rankin, PhD, a CDC epidemiologist, and colleagues outlined the trends in carbapenemase-producing CRE (CP-CRE) clinical isolates reported to the Antimicrobial Resistance Laboratory Network of the CDC from January 2019 through December 2023. In 2024, the number of NDM-positive CRE cases surpassed the number of KPC-positive CRE cases, which remained relatively stable during the study period, according to a report by Katelynn Devinney, MPH, of the New York City Department of Health and Mental Hygiene, New York City, and colleagues. Why Tracking Is Important Tracking the NDM-CRE is important, given the transmission in both healthcare settings and the community, said Gonzalo Bearman, MD, professor of medicine and chair of the Division of Infectious Diseases at Virginia Commonwealth University, Richmond, Virginia, in an interview.