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Researchers have successfully developed a new Strep A human challenge model, paving the way to test vaccines against the common deadly bacteria that causes sore throats, scarlet fever and skin sores. The collaborative research effort, led by the Murdoch Children's Research Institute (MCRI) and published in The Lancet Microbe, found the model, which deliberately infected healthy adult volunteers with the bacteria in a controlled environment, was safe and would now be used to trial Strep A candidate vaccines.