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For decades, the primary focus for reducing the prevalence of Chlamydia trachomatis in the U.S. has been on screening young women, as pelvic inflammatory disease, infertility, and ectopic pregnancy are associated with the condition. When paired with partner notification, a female-centric approach has proven cost effective, but has not really moved the needle on chlamydia prevalence rates -- the CDC still estimated about 1.8 million cases in the U.S. in 2018. On the other hand, men account for 40% of reported chlamydia infections, and likely serve as a reservoir of infection" for female sexual partners, but there are less data on the cost-effectiveness of screening men." For decades, the primary focus for reducing the prevalence of Chlamydia trachomatis in the U.S. has been on screening young women, as pelvic inflammatory disease, infertility, and ectopic pregnancy are associated with the condition. When paired with partner notification, a female-centric approach has proven cost effective, but has not really moved the needle on chlamydia prevalence rates -- the CDC still estimated about 1.8 million cases in the U.S. in 2018. On the other hand, men account for 40% of reported chlamydia infections, and likely serve as a "reservoir of infection" for female sexual partners, but there are less data on the cost-effectiveness of screening men.