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Resistance to a last-resort antibiotic in an already multidrug-resistant (MDR) bacterial pathogen is concerningly high in Africa, according to a study published last week in JAC-Antimicrobial Resistance. In a systematic review and meta-analysis, researchers from Woldia University in Ethiopia examined data from 30 studies that reported on colistin resistance in clinical specimens of MDR Klebsiella pneumoniae collected from hospitals in Africa. With mortality rates ranging from 40% to 70%, MDR K pneumoniae has been identified as a high-priority global health threat by the World Health Organization. Colistin is one of the few remaining options for treating MDR K pneumoniae infections.