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Most countries have endorsed a national action plan (NAP) on antimicrobial resistance. We previously used a governance framework to assess NAPs on antimicrobial resistance available for the period of 2020–21 from 114 countries, finding substantial variation worldwide in the commitment of resources to address an escalating global health challenge. We sought to expand and advance this analysis to include the NAPs of more low-income and middle-income countries, to cover the period of 2021–22, and to examine the strength of NAPs to address antimicrobial resistance.