Abstract
Individuals with diabetes mellitus frequently develop severe skin and soft tissue infections (SSTIs) that are recalcitrant to antibiotic treatment. [cite: 13706] We examined how diabetes affects the emergence of antibiotic resistance in a Staphylococcus aureus SSTI. We determined that S. aureus evolves antibiotic resistance rapidly in diabetic mice, while resistance did not occur in nondiabetic mice over the course of infection. [cite: 13707, 13708]
Key Data
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Publication Date12 February 2025
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Primary AuthorJohn C. Shook
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SourceScience Advances
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LanguageEnglish
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